| 1. |
EXECUTIVE SUMMARY & CONCLUSIONS |
| 1.1. |
Why Might Electronic Products in Healthcare Need to be Flexible? |
| 1.2. |
Broader Successes When Competing on More Than Cost |
| 1.3. |
Healthcare Spending is Rising Around the World |
| 1.4. |
Remote Care of Patients is on the Rise |
| 1.5. |
The Outlook for Remote Patient Monitoring – a Key Market for Printed Electronics in Healthcare |
| 1.6. |
Electronic Skin Patches |
| 1.7. |
E-Textiles |
| 1.8. |
Electrochemical Test Strips |
| 1.9. |
Smart Packaging |
| 1.10. |
Stretchable Electronics: Where is the Money So Far? |
| 1.11. |
Change in Form Factor Supported by Flexible Sensors |
| 1.12. |
Market Forecast: Flexible Electronics in Healthcare |
| 2. |
INTRODUCTION |
| 2.1.1. |
Report Scope |
| 2.1.2. |
Why Might Electronic Products in Healthcare Need to be Flexible? |
| 2.1.3. |
What is Printed, Flexible, Organic Electronics? |
| 2.1.4. |
Cost Reduction Has Been Commercially Successful |
| 2.1.5. |
Broader Successes When Competing on More Than Cost |
| 2.1.6. |
Creating New Markets |
| 2.1.7. |
Change in Form Factor Supported by Flexible Sensors |
| 2.1.8. |
Printed and Flexible Electronics Applied to Healthcare Products |
| 2.1.9. |
Examples of Flexible Electronics in Healthcare |
| 2.2. |
Trends in Healthcare Supporting Flexible Electronics |
| 2.2.1. |
Healthcare Spending is Rising Around the World |
| 2.2.2. |
Mobile Health is Becoming the Norm |
| 2.2.3. |
Consumer-Driven, Patient Centered Healthcare |
| 2.2.4. |
Remote Care of Patients is on the Rise |
| 2.2.5. |
From Connected to Wearable |
| 2.2.6. |
Skin Patches are Emerging as a Key Form Factor |
| 2.2.7. |
Medical Adherence is a Billion-Dollar Opportunity |
| 2.2.8. |
The Outlook for Remote Patient Monitoring – a Key Market for Printed Electronics in Healthcare |
| 3. |
MARKET FORECASTS |
| 3.1. |
Methodology and Assumptions |
| 3.2. |
Market Forecast: Flexible Electronics in Healthcare |
| 3.3. |
Market Forecast: Flexible Electronics in Skin Patches for Healthcare Applications |
| 3.4. |
Market Forecast: Flexible Electronics in E-Textiles for Healthcare Applications |
| 3.5. |
Market Forecast: Flexible Electronics in Other Product Types for Healthcare Applications |
| 4. |
HEALTHCARE PRODUCTS USING FLEXIBLE ELECTRONICS |
| 4.1. |
Electronic Skin Patches |
| 4.1.1. |
Definitions and Exclusions |
| 4.1.2. |
Electronic Skin Patches |
| 4.1.3. |
The Case for Skin Patches: Improving Device Form Factor |
| 4.1.4. |
Application Overview |
| 4.1.5. |
Skin Patches Competing with Established Products |
| 4.1.6. |
New Market Creation Around Skin Patches |
| 4.1.7. |
Ambulatory Cardiac Monitoring |
| 4.1.8. |
Economic and Healthcare Costs of Cardiovascular Disease |
| 4.1.9. |
Cardiovascular Monitoring Via Wearable Devices |
| 4.1.10. |
Towards Ambulatory Cardiac Monitoring |
| 4.1.11. |
Differentiation Between Ambulatory Cardiac Monitors |
| 4.1.12. |
Wearable vs Implantable Monitoring |
| 4.1.13. |
Wearable, Ambulatory Cardiac Monitoring: Comparison of Over 35 Players |
| 4.1.14. |
Printed Electronics in Cardiac Skin Patches |
| 4.1.15. |
Cardiac Skin Patch Types: Traditional Holter Monitor / Other Wired Options |
| 4.1.16. |
Cardiac Skin Patch Types: Cordless Patch with Snap Fasteners |
| 4.1.17. |
Cardiac Skin Patch Types: Flexible Patch with Integrated Electrodes |
| 4.1.18. |
Conclusions: Cardiac Monitoring Skin Patches |
| 4.1.19. |
iRhythm: ZIO |
| 4.1.20. |
Byteflies & Quad Industries |
| 4.1.21. |
DMS Service |
| 4.1.22. |
QT Medical |
| 4.1.23. |
Conclusions: Cardiac Monitoring Skin Patches Market |
| 4.1.24. |
Inpatient Monitoring |
| 4.1.25. |
Inpatient Monitoring: The Case for Removing the Wires |
| 4.1.26. |
Skin Patches for Inpatient Monitoring |
| 4.1.27. |
Sensium (Surgical Company Group) |
| 4.1.28. |
VitalConect |
| 4.1.29. |
Isansys Lifecare |
| 4.1.30. |
Leaf Healthcare |
| 4.1.31. |
Moving Outside the Hospital |
| 4.1.32. |
LifeSignals |
| 4.1.33. |
MC10 |
| 4.1.34. |
Conclusions & Related Areas |
| 4.1.35. |
Conclusions – Patient monitoring |
| 4.1.36. |
Diabetes Management |
| 4.1.37. |
The Cost of Diabetes |
| 4.1.38. |
Diabetes Management Process |
| 4.1.39. |
Diabetes Management Device Roadmap: Glucose Sensors |
| 4.1.40. |
Skin Patches for Diabetes Management |
| 4.1.41. |
CGM: Overview of key players |
| 4.1.42. |
Abbott: FreeStyle Libre |
| 4.1.43. |
Dexcom |
| 4.1.44. |
Medtronic |
| 4.1.45. |
Diabetes Management Device Roadmap: Insulin Delivery |
| 4.1.46. |
Insulin Pumps: Introduction |
| 4.1.47. |
Insulin Pumps Currently Available |
| 4.1.48. |
Insulin Patch Pumps |
| 4.1.49. |
Today: Hybrid Closed Loop Systems |
| 4.1.50. |
The Future: Closing the Feedback Loop |
| 4.1.51. |
Conclusions – Diabetes Management |
| 4.1.52. |
Temperature |
| 4.1.53. |
Approaches and Standards for Medical Temperature Sensing |
| 4.1.54. |
Skin Patches for Temperature Sensing |
| 4.1.55. |
Skin Patch Temperature Sensing: Use Cases Across 12 Case Studies |
| 4.1.56. |
VivaLNK |
| 4.1.57. |
Blue Spark |
| 4.1.58. |
Life Science Technology |
| 4.1.59. |
Isansys Lifecare |
| 4.1.60. |
Conclusions: Temperature Sensing |
| 4.1.61. |
Motion |
| 4.1.62. |
Introduction |
| 4.1.63. |
Applications for Skin Patch Motion Sensors |
| 4.1.64. |
Case Study – Concussion Detection |
| 4.1.65. |
X2 Biosystems |
| 4.1.66. |
US Military Head Trauma Patch / PARC |
| 4.1.67. |
Triax |
| 4.1.68. |
Conclusions: Motion sensing |
| 4.2. |
E-Textiles |
| 4.2.1. |
Introduction |
| 4.2.2. |
E-textiles: Where Textiles Meet Electronics |
| 4.2.3. |
Commercial Progress with E-textile Projects |
| 4.2.4. |
Types of Revenue |
| 4.2.5. |
Smart Clothing for Sports Used to be the Major Focus |
| 4.2.6. |
Medical & Healthcare |
| 4.2.7. |
Wound Care with E-textiles |
| 4.2.8. |
Urinary Incontinence |
| 4.2.9. |
Example: LifeSense Group |
| 4.2.10. |
Beyond Apparel |
| 4.2.11. |
Patient Monitoring Using E-textiles |
| 4.2.12. |
Bedsore / Pressure Ulcer Prevention |
| 4.2.13. |
Example: Sensing Tex |
| 4.2.14. |
Side-effect Management for Diabetes |
| 4.2.15. |
Bonbouton |
| 4.2.16. |
Measuring Gait |
| 4.2.17. |
Industry Challenges for E-textiles |
| 4.2.18. |
Case Study: Biometric Monitoring in Apparel |
| 4.2.19. |
Integrating HRM into Clothing |
| 4.2.20. |
Companies with Biometric Monitoring Apparel Products |
| 4.2.21. |
Sensors Used in Smart Clothing for Biometrics |
| 4.2.22. |
Example: ChronoLife |
| 4.2.23. |
Example: Hexoskin |
| 4.2.24. |
Example: Myant |
| 4.2.25. |
Example: Xenoma |
| 4.3. |
Test strips and In-Vitro Diagnostics |
| 4.3.1. |
Flexible Electronics in In-vitro Diagnostics |
| 4.3.2. |
Diabetes Management Device Roadmap: Glucose Sensors |
| 4.3.3. |
Anatomy of a Test Strip |
| 4.3.4. |
Manufacturing steps of Lifescan Ultra |
| 4.3.5. |
Profitability in the Test Strip Industry is Falling |
| 4.3.6. |
Strategy comparison amongst the largest players |
| 4.3.7. |
Electrochemical test strips: cholesterol detection |
| 4.3.8. |
Cholesterol electrochemical test strips – Key players |
| 4.3.9. |
Other electrochemical test strips for CVD |
| 4.3.10. |
Conclusions: IVD & Test Strips |
| 4.4. |
Smart Packaging |
| 4.4.1. |
Introduction: Smart packaging & logistics in healthcare |
| 4.4.2. |
Sensors in Smart Packaging – What problems are we fixing? |
| 4.4.3. |
RFID Sensors: main choices |
| 4.4.4. |
Examples of Battery Assisted Passive (BAP) RFID sensors |
| 4.4.5. |
Three main markets in the data logger business today |
| 4.4.6. |
Conclusions: Smart packaging as an application for flexible electronics in healthcare |
| 4.4.7. |
Case Study: Medication Compliance |
| 4.4.8. |
The Problem: Medication Non-Compliance – Statistics |
| 4.4.9. |
The current solution |
| 4.4.10. |
The printed electronics / RFID solutions |
| 4.4.11. |
Trial scenarios with smart blister packs |
| 4.4.12. |
Smart blister packs – not a big success yet |
| 4.4.13. |
Things are changing & more players enter |
| 5. |
TECHNOLOGY OVERVIEW AND DEVELOPMENT |
| 5.1.1. |
Stretchable Electronics: Where is the Money So Far? |
| 5.1.2. |
Design Trends to Accommodate Stretchable Electronics |
| 5.2. |
Stretchable Substrates |
| 5.2.1. |
Characterising a Stretchable Substrate |
| 5.2.2. |
Substrate Choice for Stretchable Electronics |
| 5.2.3. |
Key Parameters for Plastic Substrates |
| 5.2.4. |
Flexible Glass |
| 5.3. |
Conductive Inks |
| 5.3.1. |
Conductive Inks |
| 5.3.2. |
Stretchable Conductive Ink Suppliers Multiply |
| 5.3.3. |
The Role of Particle Size and Resin in Stretchable Inks |
| 5.3.4. |
Washability for Stretchable Conductive Inks |
| 5.3.5. |
Encapsulation Choice for Stretchable Inks |
| 5.3.6. |
The Role of the Encapsulant in Supressing Resistivity Changes |
| 5.3.7. |
Graphene-based Stretchable Conductive Inks |
| 5.4. |
Flexible Circuits |
| 5.4.1. |
Stretchable or Extremely Flexible Circuit Boards |
| 5.4.2. |
Examples of Thin and Flexible PCBs in Wearable and Display Applications |
| 5.4.3. |
Stretchable Meandering Interconnects |
| 5.4.4. |
Stretchable Printed Circuits Boards |
| 5.4.5. |
Examples of Circuits on Stretchable PCBs |
| 5.4.6. |
The Role of Pattern Design in Stretchable Conductive Inks |
| 5.4.7. |
Stretchable Printed Electronic Circuits/Systems |
| 5.4.8. |
Circuits Printed with Conductive Inks |
| 5.5. |
Printed and Flexible Sensors |
| 5.5.1. |
Sensors: Key Trends |
| 5.5.2. |
Main Benefits of Flexible and Printed Sensors |
| 5.5.3. |
Types of Sensors that can be Printed |
| 5.5.4. |
Sensors: Technology Readiness |
| 5.5.5. |
Electrodes |
| 5.5.6. |
Introduction – Measuring biopotential |
| 5.5.7. |
Technology Overview – The Circuitry for Measuring Biopotential |
| 5.5.8. |
Textile Electrodes |
| 5.5.9. |
Technology Overview – Electrode Properties |
| 5.5.10. |
Temperature Sensors |
| 5.5.11. |
Printed Temperature Sensors |
| 5.5.12. |
Printed Thermistors Enable New Designs |
| 5.5.13. |
Temperature Sensing Technology Options |
| 5.5.14. |
Biosensors |
| 5.5.15. |
Anatomy of a test strip: one example |
| 5.5.16. |
Manufacturing Steps Of Lifescan Ultra |
| 5.5.17. |
Inks for Biosensors |
| 5.5.18. |
Force / Pressure Sensors |
| 5.5.19. |
Technology Overview – Resistive/Piezoresistive Sensing |
| 5.5.20. |
Force Sensing Resistors |
| 5.5.21. |
Materials |
| 5.5.22. |
Printed Piezoresistive Sensor |
| 5.5.23. |
Technology Overview – Piezoelectric Sensing |
| 5.5.24. |
Technology Overview – Capacitive Sensing |
| 5.5.25. |
Others |
| 5.5.26. |
Moisture Sensors |
| 5.6. |
E-Textiles |
| 5.6.1. |
Electronic Textiles (E-Textiles) |
| 5.6.2. |
Strategies for Creating Textile-integrated Electronics |
| 5.6.3. |
Challenges When Moving into the E-textiles Space |
| 5.6.4. |
Materials and Components |
| 5.6.5. |
Fibres & Yarns |
| 5.6.6. |
Examples of Traditional Conductive Fibres |
| 5.6.7. |
Hybrid Yarns can be Conductive, Elastic and Comfortable |
| 5.6.8. |
Electronic Components Integrated into Yarns |
| 5.6.9. |
Textiles and Fabrics |
| 5.6.10. |
Stretchable Electronic Fabrics |
| 5.6.11. |
Connectors for E-textiles |
| 5.6.12. |
Textile Cabling |
| 5.6.13. |
Metal Wiring Integrated into Textiles |
| 5.6.14. |
Inks and Encapsulation |
| 5.6.15. |
Novel Approaches to Conductive Textiles: CNT & Graphene |
| 5.6.16. |
Challenges with Conductive Inks in E-textiles |
| 5.6.17. |
Conductive Polymers |
| 5.6.18. |
Carbon Rubbers as Electrodes in Compression Garments |
| 5.6.19. |
E-textile Material Use Today |
| 5.6.20. |
Example suppliers for each material type |
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